New Initiative on Glaucoma Research
Wednesday, 30 April 2014 11:56
(In conjunction with the Breed Council and other Dandie breed clubs)

Dear Member,

Whilst that research ongoing in Finland by Professor Lohi started 6 years ago to find the DNA marker for Glaucoma within our breed is still ongoing. It is hoped that this new research being conducted by The Animal Heath Trust will be a valuable addition. The AHT is based in the Kennel Club Genetics Centre and this project is being funded by Dogs Trust.

It will be done by James Oliver, European Specialist in Veterinary Ophthalmology. Previous research, has already identified one gene significantly associated with glaucoma in one of the other breeds under investigation. 

Dandie Dinmont Terriers are now to be included in the project and James is asking for samples to be taken, via cheek swabs, from Dandies who have developed Glaucoma; Dandies diagnosed as being affected by goniodysgenesis(predisposition for glaucoma); also Dandies certified with normal eyes at the age of 5 years or more.  If you are willing to contribute samples from your Dandie please contact James Oliver via e mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it . ?This will be treated in confidence.

We will be inviting James Oliver to our events over the next couple of years. He will conduct eye testing, previously booked where required and also do DNA swab tests. The first of which being our July 13th 2014 Championship Show. So please bring along your Dandies even if they are not being shown that day, regardless of age and whether or not they have previously had an eye examination. 

Now what can you do to help this study? If you have a Dandie which fits the descriptions above please either contact James directly for a cheek swab collection pack or bring him/her to one of the testing days (more details will follow nearer the time to book your place). Furthermore, should you know of any Dandies not in your ownership that might be suitable for inclusion in the study, then please encourage the owners to contact James directly or attend one of the testing days even though they may not be a member of the DDTC.

We do hope our members and visitors to this site who have Dandies will support this new important research.  

Below copy of Letter from Mr James Oliver BVSc CertVOphthal DipECVO MRCVS


2nd April 2014
Dear Dandie Dinmont Terrier Owner 
At the Animal Health Trust, a study is being carried out to investigate the genetic basis of glaucoma in the Dandie Dinmont Terrier with sample collection funded by a grant from Dogs Trust. This research will hopefully lead to an improved understanding of this painful and blinding disease, and will enable us to develop a DNA test that breeders can use to help eliminate this serious condition from the breed.  I am currently collecting samples for this study, in the form of cheek swabs, from dogs with glaucoma, dogs with goniodysgenesis (as diagnosed by an ophthalmologist), and dogs certified with normal eyes at the age of 5 years or above. 
If you would be willing to contribute samples from your dog (or any other of your dogs), please could you contact me (preferably by email) and I will be able to give you specific details and send a swab collection kit. If you have already submitted a DNA sample from your dog to the AHT then please get in touch as we may just require some additional information for the study. Please be assured that confidentiality will be preserved and we will not pass your details on to any third party outside the Animal Health Trust.
Yours sincerely 
James Oliver BVSc CertVOphthal DipECVO MRCVS
European Specialist in Veterinary Ophthalmology                                             
Centre for Small Animal Studies             
Animal Health Trust, Lanwades Park                                            
Kentford, Newmarket  Suffolk CB8 7UU                                      
Tel: 01638 552700 ext.1381                         
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it